Naturally, there must be a physical examination and laboratory tests. Pulmonary function tests may yield useful data to confirm or exclude the diagnosis of work-related asthma. Moreover, the methacholine challenge test will assess airway hyperresponsiveness through provocation. This entails injection of a substance which induces airway hyperreactivity, and the physician observes how long it takes before the patient has that reaction [1, 3].
Though non-specific airway hyperresponsiveness may occur from provocation testing with methacholine, mannitol, adenosine, or histamine, this finding is not diagnostic of occupational asthma [1, 3].
Hence, there must be a test that produces a reaction from the agent which is responsible for the symptoms of work-related asthma. In essence, this confirms the diagnosis [1].


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