The Youtube video provides a good overview about Closys from the medical perspective. It is highly endorsed by dentists as a good mouthwash for overal oral care.
If you have tried Profresh, Profresh recommends that you gargle before brushing your teeth, and after brushing your teeth. Closys did not specify exactly when to gargle, but like most mouthwashes, people typically gargle after brushing their teeth.
From my experience, whether before or after brushing, Closys seems to work equally effectively. Interestingly, the minty toothpaste residual taste was not present even when I gargled before brushing my teeth. For people who like their breath to be completely odorless (as opposed to minty fresh), this might be of interest to you.
Morning Breath and Closys
If you suffer from morning breath, Closys does a good job of de-intensifying that condition. If you have post-nasal drip, it definitely helps, but does not completely eliminate morning breath, especially since our mouths are drier at night due to less saliva production.
Dry Mouth, Post-Nasal Drip and Closys
As the day wears on, your breath may not feel as fresh as it was after you first used Closys. Drinking water helps oxygen-rich saliva production, but it also helps to keep your breath smelling fresh. If you have post-nasal drip, and dry mouth, Closys will help to manage the odor, but you will slowly start to taste or feel that your breath is not as odorless anymore.
Drinking water is a very good way to ensure that the effects of Closys are prolonged and are not immediately snuffed out by mucus dripping at the back of the throat.
Tonsil Stones and Closys
Tonsil stones can be a real pain - both a pain in the throat, but also a pain to manage. If they are small enough, they will be hardly noticeable in your breath. Unlike Therabreath that can be swallowed, Closys is not meant to be digested. But if you are able to dislodge these tonsil stones gently using a q-tip, you should not have to worry about them too much.